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Single-Channel Characteristics of Wild-Type I(Ks) Channels and Channels formed with Two MinK Mutants that Cause Long QT Syndrome

I(Ks) channels are voltage dependent and K(+) selective. They influence cardiac action potential duration through their contribution to myocyte repolarization. Assembled from minK and KvLQT1 subunits, I(Ks) channels are notable for a heteromeric ion conduction pathway in which both subunit types con...

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Detalles Bibliográficos
Autores principales: Sesti, Federico, Goldstein, Steve A.N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229448/
https://www.ncbi.nlm.nih.gov/pubmed/9834138