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Localization of the K(+) Lock-in and the Ba(2+) Binding Sites in a Voltage-Gated Calcium-Modulated Channel: Implications for Survival of K(+) Permeability
Using Ba(2+) as a probe, we performed a detailed characterization of an external K(+) binding site located in the pore of a large conductance Ca(2+)-activated K(+) (BK(Ca)) channel from skeletal muscle incorporated into planar lipid bilayers. Internal Ba(2+) blocks BK(Ca) channels and decreasing ext...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229454/ https://www.ncbi.nlm.nih.gov/pubmed/10469727 |