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Gat1 (Gaba:Na(+):Cl(−)) Cotransport Function: Kinetic Studies in Giant Xenopus Oocyte Membrane Patches
To explain cotransport function, the “alternating access” model requires that conformational changes of the empty transporter allow substrates to bind alternatively on opposite membrane sides. To test this principle for the GAT1 (GABA:Na(+):Cl(−)) cotransporter, we have analyzed how its charge-movin...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229455/ https://www.ncbi.nlm.nih.gov/pubmed/10469734 |