Regulation of Hyperpolarization-Activated Hcn Channel Gating and Camp Modulation Due to Interactions of Cooh Terminus and Core Transmembrane Regions

Members of the hyperpolarization-activated cation (HCN) channel family generate HCN currents (I(h)) that are directly regulated by cAMP and contribute to pacemaking activity in heart and brain. The four different HCN isoforms show distinct biophysical properties. In cell-free patches from Xenopus oo...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Chen, Shan, Siegelbaum, Steven A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229504/
https://www.ncbi.nlm.nih.gov/pubmed/11524455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229504/
https://www.ncbi.nlm.nih.gov/pubmed/11524455

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