Calmodulin Binding to the 3614–3643 Region of RyR1 Is Not Essential for Excitation–Contraction Coupling in Skeletal Myotubes

Calmodulin is a ubiquitous Ca(2+) binding protein that modulates the in vitro activity of the skeletal muscle ryanodine receptor (RyR1). Residues 3614–3643 of RyR1 comprise the CaM binding domain and mutations within this region result in a loss of both high-affinity Ca(2+)-bound calmodulin (CaCaM)...

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Detalles Bibliográficos
Autores principales: O'Connell, Kristen M.S., Yamaguchi, Naohiro, Meissner, Gerhard, Dirksen, Robert T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229515/
https://www.ncbi.nlm.nih.gov/pubmed/12198090
http://dx.doi.org/10.1085/jgp.20028617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229515/
https://www.ncbi.nlm.nih.gov/pubmed/12198090
http://dx.doi.org/10.1085/jgp.20028617

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