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Coupling between Voltage Sensor Activation, Ca(2+) Binding and Channel Opening in Large Conductance (BK) Potassium Channels
To determine how intracellular Ca(2+) and membrane voltage regulate the gating of large conductance Ca(2+)-activated K(+) (BK) channels, we examined the steady-state and kinetic properties of mSlo1 ionic and gating currents in the presence and absence of Ca(2+) over a wide range of voltage. The acti...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229516/ https://www.ncbi.nlm.nih.gov/pubmed/12198087 http://dx.doi.org/10.1085/jgp.20028605 |