Mechanism of Tacrine Block at Adult Human Muscle Nicotinic Acetylcholine Receptors

We used single-channel kinetic analysis to study the inhibitory effects of tacrine on human adult nicotinic receptors (nAChRs) transiently expressed in HEK 293 cells. Single channel recording from cell-attached patches revealed concentration- and voltage-dependent decreases in mean channel open prob...

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Detalles Bibliográficos
Autores principales: Prince, Richard J., Pennington, Richard A., Sine, Steven M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229521/
https://www.ncbi.nlm.nih.gov/pubmed/12198092
http://dx.doi.org/10.1085/jgp.20028583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229521/
https://www.ncbi.nlm.nih.gov/pubmed/12198092
http://dx.doi.org/10.1085/jgp.20028583

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