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Slow Inactivation Does Not Block the Aqueous Accessibility to the Outer Pore of Voltage-gated Na Channels

Slow inactivation of voltage-gated Na channels is kinetically and structurally distinct from fast inactivation. Whereas structures that participate in fast inactivation are well described and include the cytoplasmic III-IV linker, the nature and location of the slow inactivation gating mechanism rem...

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Detalles Bibliográficos
Autores principales: Struyk, Arie F., Cannon, Stephen C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229532/
https://www.ncbi.nlm.nih.gov/pubmed/12356853
http://dx.doi.org/10.1085/jgp.20028672