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Extracellular Sodium Interacts with the HERG Channel at an Outer Pore Site

Most voltage-gated K(+) currents are relatively insensitive to extracellular Na(+) (Na(+) (o)), but Na(+) (o) potently inhibits outward human ether-a-go-go–related gene (HERG)–encoded K(+) channel current (Numaguchi, H., J.P. Johnson, Jr., C.I. Petersen, and J.R. Balser. 2000. Nat. Neurosci. 3:429–3...

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Detalles Bibliográficos
Autores principales: Mullins, Franklin M., Stepanovic, Svetlana Z., Desai, Reshma R., George, Alfred L., Balser, Jeffrey R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229534/
https://www.ncbi.nlm.nih.gov/pubmed/12356854
http://dx.doi.org/10.1085/jgp.20028589