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External TEA Block of Shaker K(+) Channels Is Coupled to the Movement of K(+) Ions within the Selectivity Filter
Recent molecular dynamic simulations and electrostatic calculations suggested that the external TEA binding site in K(+) channels is outside the membrane electric field. However, it has been known for some time that external TEA block of Shaker K(+) channels is voltage dependent. To reconcile these...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229542/ https://www.ncbi.nlm.nih.gov/pubmed/12885878 http://dx.doi.org/10.1085/jgp.200308848 |