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Transport Function of the Renal Type IIa Na(+)/P(i) Cotransporter Is Codetermined by Residues in Two Opposing Linker Regions

Two highly similar regions in the predicted first intracellular (ICL-1) and third extracellular loop (ECL-3) of the type IIa Na(+)/Pi cotransporter (NaPi-IIa) have been shown previously to contain functionally important sites by applying the substituted cysteine accessibility method (SCAM). Incubati...

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Detalles Bibliográficos
Autores principales: Köhler, Katja, Forster, Ian C., Stange, Gerti, Biber, Jürg, Murer, Heini
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229554/
https://www.ncbi.nlm.nih.gov/pubmed/12407080
http://dx.doi.org/10.1085/jgp.20028645