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Structural and Functional Role of the Extracellular S5-P Linker in the HERG Potassium Channel

C-type inactivation in the HERG channel is unique among voltage-gated K channels in having extremely fast kinetics and strong voltage sensitivity. This suggests that HERG may have a unique outer mouth structure (where conformational changes underlie C-type inactivation), and/or a unique communicatio...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Zhang, Mei, Jiang, Min, Tseng, Gea-Ny
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229555/
https://www.ncbi.nlm.nih.gov/pubmed/12407082
http://dx.doi.org/10.1085/jgp.20028687