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Structural and Functional Role of the Extracellular S5-P Linker in the HERG Potassium Channel
C-type inactivation in the HERG channel is unique among voltage-gated K channels in having extremely fast kinetics and strong voltage sensitivity. This suggests that HERG may have a unique outer mouth structure (where conformational changes underlie C-type inactivation), and/or a unique communicatio...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229555/ https://www.ncbi.nlm.nih.gov/pubmed/12407082 http://dx.doi.org/10.1085/jgp.20028687 |