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The Role of Loop 5 in Acetylcholine Receptor Channel Gating

Nicotinic acetylcholine receptor channel (AChR) gating is an organized sequence of molecular motions that couples a change in the affinity for ligands at the two transmitter binding sites with a change in the ionic conductance of the pore. Loop 5 (L5) is a nine-residue segment (mouse α-subunit 92–10...

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Detalles Bibliográficos
Autores principales: Chakrapani, Sudha, Bailey, Timothy D., Auerbach, Anthony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229574/
https://www.ncbi.nlm.nih.gov/pubmed/14557402
http://dx.doi.org/10.1085/jgp.200308885