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The Role of Loop 5 in Acetylcholine Receptor Channel Gating
Nicotinic acetylcholine receptor channel (AChR) gating is an organized sequence of molecular motions that couples a change in the affinity for ligands at the two transmitter binding sites with a change in the ionic conductance of the pore. Loop 5 (L5) is a nine-residue segment (mouse α-subunit 92–10...
Autores principales: | Chakrapani, Sudha, Bailey, Timothy D., Auerbach, Anthony |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229574/ https://www.ncbi.nlm.nih.gov/pubmed/14557402 http://dx.doi.org/10.1085/jgp.200308885 |
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