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Voltage-dependent Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Cl(−) Channel

When excised inside-out membrane patches are bathed in symmetrical Cl(−)-rich solutions, the current-voltage (I-V) relationship of macroscopic cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) currents inwardly rectifies at large positive voltages. To investigate the mechanism of inwa...

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Detalles Bibliográficos
Autores principales: Cai, Zhiwei, Scott-Ward, Toby S., Sheppard, David N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229579/
https://www.ncbi.nlm.nih.gov/pubmed/14581585
http://dx.doi.org/10.1085/jgp.200308921