Cargando…

Voltage-dependent Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Cl(−) Channel

When excised inside-out membrane patches are bathed in symmetrical Cl(−)-rich solutions, the current-voltage (I-V) relationship of macroscopic cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) currents inwardly rectifies at large positive voltages. To investigate the mechanism of inwa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Zhiwei, Scott-Ward, Toby S., Sheppard, David N.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229579/ https://www.ncbi.nlm.nih.gov/pubmed/14581585 http://dx.doi.org/10.1085/jgp.200308921

Ejemplares similares

Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates
Publicado: (1993)

The Mechanistic Links between Insulin and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Cl(−) Channel
por: Marunaka, Yoshinori
Publicado: (2017)

Nonequilibrium gating and voltage dependence of the ClC-0 Cl- channel
Publicado: (1996)

Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains
por: Csanády, László, et al.
Publicado: (2000)

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): THREE-DIMENSIONAL STRUCTURE AND LOCALIZATION OF A CHANNEL GATE
por: Rosenberg, Mark F., et al.
Publicado: (2011)

Dual Activity of Aminoarylthiazoles on the Trafficking and Gating Defects of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Caused by Cystic Fibrosis Mutations
por: Pedemonte, Nicoletta, et al.
Publicado: (2011)

Role of the Juxtamembrane Region of Cytoplasmic Loop 3 in the Gating and Conductance of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
por: El Hiani, Yassine, et al.
Publicado: (2012)

Role of ATP binding and hydrolysis in the gating of the cystic fibrosis transmembrane conductance regulator
por: Gout, Taras
Publicado: (2012)

Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
por: Wang, Wuyang, et al.
Publicado: (2011)

Role of Transmembrane Segment S5 on Gating of Voltage-dependent K(+) Channels
por: Shieh, Char-Chang, et al.
Publicado: (1997)

Gating of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels by Adenosine Triphosphate Hydrolysis : Quantitative Analysis of a Cyclic Gating Scheme
por: Zeltwanger, Shawn, et al.
Publicado: (1999)

Actions of Genistein on Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating : Evidence for Two Binding Sites with Opposite Effects
por: Wang, Fei, et al.
Publicado: (1998)

Probes of the conduction process of a voltage-gated Cl- channel from Torpedo electroplax
Publicado: (1981)

Molecular dynamics study of Cl(−) permeation through cystic fibrosis transmembrane conductance regulator (CFTR)
por: Zeng, Zhi Wei, et al.
Publicado: (2023)

A Role for the S0 Transmembrane Segment in Voltage-dependent Gating of BK Channels
por: Koval, Olga M., et al.
Publicado: (2007)

Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator
por: Villamizar, Olga, et al.
Publicado: (2019)

Adenosine Triphosphate–dependent Asymmetry of Anion Permeation in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
por: Linsdell, Paul, et al.
Publicado: (1998)

Glycosylation and the cystic fibrosis transmembrane conductance regulator
por: Scanlin, Thomas F, et al.
Publicado: (2001)

Where Is the Cystic Fibrosis Transmembrane Conductance Regulator?
por: Barbry, Pascal, et al.
Publicado: (2021)

Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives
por: Schmidt, Béla Z, et al.
Publicado: (2016)

The Extrapulmonary Effects of Cystic Fibrosis Transmembrane Conductance Regulator Modulators in Cystic Fibrosis
por: Sergeev, Valentine, et al.
Publicado: (2020)

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): CLOSED AND OPEN STATE CHANNEL MODELS
por: Corradi, Valentina, et al.
Publicado: (2015)

Acquired cystic fibrosis transmembrane conductance regulator dysfunction
por: Banks, Catherine, et al.
Publicado: (2018)

Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR
por: Bose, Samuel J., et al.
Publicado: (2019)

Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits
por: Sun, Xiaohui, et al.
Publicado: (2012)

Cystic fibrosis transmembrane conductance regulator mutations at a referral center for cystic fibrosis
por: Coutinho, Cyntia Arivabeni de Araújo Correia, et al.
Publicado: (2013)

Two Small Molecules Restore Stability to a Subpopulation of the Cystic Fibrosis Transmembrane Conductance Regulator with the Predominant Disease-causing Mutation
por: Meng, Xin, et al.
Publicado: (2017)

Halide Permeation in Wild-Type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels
por: Tabcharani, Joseph A., et al.
Publicado: (1997)

Locating the Anion-selectivity Filter of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel
por: Cheung, Min, et al.
Publicado: (1997)

666 Ivacaftor boosts cystic fibrosis transmembrane conductance regulator–mediated nasal potential difference in cystic fibrosis transmembrane conductance regulator knockout mice treated with human cystic fibrosis transmembrane conductance regulator messenger ribonucleic acid lipid nanoparticle
por: Mukherjee, A., et al.
Publicado: (2022)

Quantitative Analysis of the Voltage-dependent Gating of Mouse Parotid ClC-2 Chloride Channel
por: de Santiago, Jose Antonio, et al.
Publicado: (2005)

The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor
por: Broadbent, Steven D., et al.
Publicado: (2014)

The cystic fibrosis transmembrane conductance regulator (CFTR) and its stability
por: Meng, Xin, et al.
Publicado: (2016)

A transistor model for the cystic fibrosis transmembrane conductance regulator
por: Hunt, William D., et al.
Publicado: (2023)

Cystic Fibrosis Transmembrane Conductance Regulator Folding Mutations Reveal Differences in Corrector Efficacy Linked to Increases in Immature Cystic Fibrosis Transmembrane Conductance Regulator Expression
por: Peters, Kathryn W., et al.
Publicado: (2021)

Permeability of Wild-Type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels to Polyatomic Anions
por: Linsdell, Paul, et al.
Publicado: (1997)

Multi-Ion Mechanism for Ion Permeation and Block in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
por: Linsdell, Paul, et al.
Publicado: (1997)

Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents
Publicado: (1992)

Cystic fibrosis transmembrane conductance regulator (CFTR): Making an ion channel out of an active transporter structure
por: Linsdell, Paul
Publicado: (2018)

HEK‐293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl(−) transport
por: Domingue, Jada C., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_sso48a8i9fpimlldobu90bp40m