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Stretch of β1 Integrin Activates an Outwardly Rectifying Chloride Current via FAK and Src in Rabbit Ventricular Myocytes

Osmotic swelling of cardiac myocytes and other types of cells activates an outwardly rectifying, tamoxifen-sensitive Cl(−) current, I(Cl,swell), but it is unclear whether Cl(−) currents also are activated by direct mechanical stretch. We tested whether specific stretch of β1-integrin activates a Cl(...

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Detalles Bibliográficos
Autores principales: Browe, David M., Baumgarten, Clive M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229598/
https://www.ncbi.nlm.nih.gov/pubmed/14610020
http://dx.doi.org/10.1085/jgp.200308899