External Barium Affects the Gating of KCNQ1 Potassium Channels and Produces a Pore Block via Two Discrete Sites

The pore properties and the reciprocal interactions between permeant ions and the gating of KCNQ channels are poorly understood. Here we used external barium to investigate the permeation characteristics of homomeric KCNQ1 channels. We assessed the Ba(2+) binding kinetics and the concentration and v...

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Detalles Bibliográficos
Autores principales: Gibor, Gilad, Yakubovich, Daniel, Peretz, Asher, Attali, Bernard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229603/
https://www.ncbi.nlm.nih.gov/pubmed/15226366
http://dx.doi.org/10.1085/jgp.200409068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229603/
https://www.ncbi.nlm.nih.gov/pubmed/15226366
http://dx.doi.org/10.1085/jgp.200409068

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