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Binding of κ-Conotoxin PVIIA to Shaker K(+) Channels Reveals Different K(+) and Rb(+) Occupancies within the Ion Channel Pore

The x-ray structure of the KcsA channel at different [K(+)] and [Rb(+)] provided insight into how K(+) channels might achieve high selectivity and high K(+) transit rates and showed marked differences between the occupancies of the two ions within the ion channel pore. In this study, the binding of...

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Detalles Bibliográficos
Autores principales: Boccaccio, Anna, Conti, Franco, Olivera, Baldomero M., Terlau, Heinrich
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229607/
https://www.ncbi.nlm.nih.gov/pubmed/15226365
http://dx.doi.org/10.1085/jgp.200409048