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Binding of κ-Conotoxin PVIIA to Shaker K(+) Channels Reveals Different K(+) and Rb(+) Occupancies within the Ion Channel Pore
The x-ray structure of the KcsA channel at different [K(+)] and [Rb(+)] provided insight into how K(+) channels might achieve high selectivity and high K(+) transit rates and showed marked differences between the occupancies of the two ions within the ion channel pore. In this study, the binding of...
Autores principales: | Boccaccio, Anna, Conti, Franco, Olivera, Baldomero M., Terlau, Heinrich |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229607/ https://www.ncbi.nlm.nih.gov/pubmed/15226365 http://dx.doi.org/10.1085/jgp.200409048 |
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