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Elimination of the Slow Gating of Clc-0 Chloride Channel by a Point Mutation
The inactivation of the ClC-0 chloride channel is very temperature sensitive and is greatly facilitated by the binding of a zinc ion (Zn(2+)) from the extracellular side, leading to a Zn(2+)-induced current inhibition. To further explore the relation of Zn(2+) inhibition and the ClC-0 inactivation,...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229640/ https://www.ncbi.nlm.nih.gov/pubmed/10398688 |