rIFN-γ-mediated growth suppression of platinum-sensitive and -resistant ovarian tumor cell lines not dependent upon arginase inhibition

BACKGROUND: Arginine metabolism in tumor cell lines can be influenced by various cytokines, including recombinant human interferon-γ (rIFN-γ), a cytokine that shows promising clinical activity in epithelial ovarian cancer (EOC). METHODS: We examined EOC cell lines for the expression of arginase in a...

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Detalles Bibliográficos
Autores principales: Melichar, Bohuslav, Hu, Wei, Patenia, Rebecca, Melicharová, Karolina, Gallardo, Stacie T, Freedman, Ralph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC222988/
https://www.ncbi.nlm.nih.gov/pubmed/14572312
http://dx.doi.org/10.1186/1479-5876-1-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC222988/
https://www.ncbi.nlm.nih.gov/pubmed/14572312
http://dx.doi.org/10.1186/1479-5876-1-5

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