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rIFN-γ-mediated growth suppression of platinum-sensitive and -resistant ovarian tumor cell lines not dependent upon arginase inhibition
BACKGROUND: Arginine metabolism in tumor cell lines can be influenced by various cytokines, including recombinant human interferon-γ (rIFN-γ), a cytokine that shows promising clinical activity in epithelial ovarian cancer (EOC). METHODS: We examined EOC cell lines for the expression of arginase in a...
Autores principales: | Melichar, Bohuslav, Hu, Wei, Patenia, Rebecca, Melicharová, Karolina, Gallardo, Stacie T, Freedman, Ralph |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC222988/ https://www.ncbi.nlm.nih.gov/pubmed/14572312 http://dx.doi.org/10.1186/1479-5876-1-5 |
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