Synergistic Activation of G Protein–Gated Inwardly Rectifying Potassium Channels by the βγ Subunits of G Proteins and Na(+) and Mg(2+) Ions

Native and recombinant G protein–gated inwardly rectifying potassium (GIRK) channels are directly activated by the βγ subunits of GTP-binding (G) proteins. The presence of phosphatidylinositol-bis-phosphate (PIP(2)) is required for G protein activation. Formation (via hydrolysis of ATP) of endogenou...

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Detalles Bibliográficos
Autores principales: Petit-Jacques, Jérôme, Sui, Jin Liang, Logothetis, Diomedes E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230539/
https://www.ncbi.nlm.nih.gov/pubmed/10532964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230539/
https://www.ncbi.nlm.nih.gov/pubmed/10532964

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