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Recombinant human activated protein C: current insights into its mechanism of action
Impairment of the protein C pathway plays a central role in the pathogenesis of sepsis. Administration of recombinant human activated protein C (rhAPC) may correct the dysregulated anticoagulant mechanism and prevent propagation of thrombin generation and formation of microvascular thrombosis. Furth...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230607/ https://www.ncbi.nlm.nih.gov/pubmed/18269690 http://dx.doi.org/10.1186/cc6154 |