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State-Dependent Inactivation of the α1g T-Type Calcium Channel

We have examined the kinetics of whole-cell T-current in HEK 293 cells stably expressing the α1G channel, with symmetrical Na(+) (i) and Na(+) (o) and 2 mM Ca(2+) (o). After brief strong depolarization to activate the channels (2 ms at +60 mV; holding potential −100 mV), currents relaxed exponential...

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Detalles Bibliográficos
Autores principales: Serrano, Jose R., Perez-Reyes, Edward, Jones, Stephen W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230639/
https://www.ncbi.nlm.nih.gov/pubmed/10435997