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An epigenetic vaccine model active in the prevention and treatment of melanoma
BACKGROUND: Numerous immune genes are epigenetically silenced in tumor cells and agents such as histone deacetylase inhibitors (HDACi), which reverse these effects, could potentially be used to develop therapeutic vaccines. The conversion of cancer cells to antigen presenting cells (APCs) by HDACi t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231344/ https://www.ncbi.nlm.nih.gov/pubmed/18070359 http://dx.doi.org/10.1186/1479-5876-5-64 |