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Spatial chemical conservation of hot spot interactions in protein-protein complexes

BACKGROUND: Conservation of the spatial binding organizations at the level of physico-chemical interactions is important for the formation and stability of protein-protein complexes as well as protein and drug design. Due to the lack of computational tools for recognition of spatial patterns of inte...

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Detalles Bibliográficos
Autores principales: Shulman-Peleg, Alexandra, Shatsky, Maxim, Nussinov, Ruth, Wolfson, Haim J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231411/
https://www.ncbi.nlm.nih.gov/pubmed/17925020
http://dx.doi.org/10.1186/1741-7007-5-43