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Inactivation of Bk Channels Mediated by the Nh(2) Terminus of the β3b Auxiliary Subunit Involves a Two-Step Mechanism: Possible Separation of Binding and Blockade

A family of auxiliary β subunits coassemble with Slo α subunit to form Ca(2)+-regulated, voltage-activated BK-type K(+) channels. The β subunits play an important role in regulating the functional properties of the resulting channel protein, including apparent Ca(2)+ dependence and inactivation. The...

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Detalles Bibliográficos
Autores principales: Lingle, Christopher J., Zeng, Xu-Hui, Ding, J.-P., Xia, Xiao-Ming
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2232400/
https://www.ncbi.nlm.nih.gov/pubmed/11382808