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Functional Coupling of the β(1) Subunit to the Large Conductance Ca(2+)-Activated K(+) Channel in the Absence of Ca(2+) : Increased Ca(2+) Sensitivity from a Ca(2+)-Independent Mechanism

Coexpression of the β(1) subunit with the α subunit (mSlo) of BK channels increases the apparent Ca(2+) sensitivity of the channel. This study investigates whether the mechanism underlying the increased Ca(2+) sensitivity requires Ca(2+), by comparing the gating in 0 Ca(2+) (i) of BK channels compos...

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Detalles Bibliográficos
Autores principales: Nimigean, Crina M., Magleby, Karl L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2232893/
https://www.ncbi.nlm.nih.gov/pubmed/10828246