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Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines

BACKGROUND: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epitopes derived from highly variable genome regions. Conversely, in a diagnostic and disease monitoring setting, epitopes tha...

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Detalles Bibliográficos
Autores principales: Bui, Huynh-Hoa, Sidney, John, Li, Wei, Fusseder, Nicolas, Sette, Alessandro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233646/
https://www.ncbi.nlm.nih.gov/pubmed/17897458
http://dx.doi.org/10.1186/1471-2105-8-361