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The Mannose Receptor Mediates Dengue Virus Infection of Macrophages

Macrophages (MØ) and mononuclear phagocytes are major targets of infection by dengue virus (DV), a mosquito-borne flavivirus that can cause haemorrhagic fever in humans. To our knowledge, we show for the first time that the MØ mannose receptor (MR) binds to all four serotypes of DV and specifically...

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Detalles Bibliográficos
Autores principales: Miller, Joanna L, deWet, Barend J. M, Martinez-Pomares, Luisa, Radcliffe, Catherine M, Dwek, Raymond A, Rudd, Pauline M, Gordon, Siamon
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233670/
https://www.ncbi.nlm.nih.gov/pubmed/18266465
http://dx.doi.org/10.1371/journal.ppat.0040017