Cargando…

Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14

The IκB kinase (IKK) complex is a key regulator of signal transduction pathways leading to the induction of NF-κB-dependent gene expression and production of pro-inflammatory cytokines. It therefore represents a major target for the development of anti-inflammatory therapeutic drugs and may be targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ron A.-J, Ryzhakov, Grigory, Cooray, Samantha, Randow, Felix, Smith, Geoffrey L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233672/
https://www.ncbi.nlm.nih.gov/pubmed/18266467
http://dx.doi.org/10.1371/journal.ppat.0040022