The Extracellular Linker of Muscle Acetylcholine Receptor Channels Is a Gating Control Element

We describe the functional consequences of mutations in the linker between the second and third transmembrane segments (M2–M3L) of muscle acetylcholine receptors at the single-channel level. Hydrophobic mutations (Ile, Cys, and Phe) placed near the middle of the linker of the α subunit (αS269) prolo...

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Detalles Bibliográficos
Autores principales: Grosman, Claudio, Salamone, Frank N., Sine, Steven M., Auerbach, Anthony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233691/
https://www.ncbi.nlm.nih.gov/pubmed/10962011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233691/
https://www.ncbi.nlm.nih.gov/pubmed/10962011

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