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The Extracellular Linker of Muscle Acetylcholine Receptor Channels Is a Gating Control Element
We describe the functional consequences of mutations in the linker between the second and third transmembrane segments (M2–M3L) of muscle acetylcholine receptors at the single-channel level. Hydrophobic mutations (Ile, Cys, and Phe) placed near the middle of the linker of the α subunit (αS269) prolo...
Autores principales: | Grosman, Claudio, Salamone, Frank N., Sine, Steven M., Auerbach, Anthony |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233691/ https://www.ncbi.nlm.nih.gov/pubmed/10962011 |
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