A Point Mutation in the Pore Region Alters Gating, Ca(2+)Blockage, and Permeation of Olfactory Cyclic Nucleotide–Gated Channels

Upon stimulation by odorants, Ca(2+) and Na(+) enter the cilia of olfactory sensory neurons through channels directly gated by cAMP. Cyclic nucleotide–gated channels have been found in a variety of cells and extensively investigated in the past few years. Glutamate residues at position 363 of the α...

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Detalles Bibliográficos
Autores principales: Gavazzo, Paola, Picco, Cristiana, Eismann, Elisabeth, Kaupp, U. Benjamin, Menini, Anna
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233693/
https://www.ncbi.nlm.nih.gov/pubmed/10962010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233693/
https://www.ncbi.nlm.nih.gov/pubmed/10962010

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