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A Point Mutation in the Pore Region Alters Gating, Ca(2+)Blockage, and Permeation of Olfactory Cyclic Nucleotide–Gated Channels
Upon stimulation by odorants, Ca(2+) and Na(+) enter the cilia of olfactory sensory neurons through channels directly gated by cAMP. Cyclic nucleotide–gated channels have been found in a variety of cells and extensively investigated in the past few years. Glutamate residues at position 363 of the α...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233693/ https://www.ncbi.nlm.nih.gov/pubmed/10962010 |