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Regulation of Cloned Atp-Sensitive K Channels by Adenine Nucleotides and Sulfonylureas: Interactions between Sur1 and Positively Charged Domains on Kir6.2

K(ATP) channels, comprised of the pore-forming protein Kir6.x and the sulfonylurea receptor SURx, are regulated in an interdependent manner by adenine nucleotides, PIP(2), and sulfonylureas. To gain insight into these interactions, we investigated the effects of mutating positively charged residues...

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Detalles Bibliográficos
Autores principales: John, Scott A., Weiss, James N., Ribalet, Bernard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233703/
https://www.ncbi.nlm.nih.gov/pubmed/11585851