Single-channel SCAM Identifies Pore-lining Residues in the First Extracellular Loop and First Transmembrane Domains of Cx46 Hemichannels

Gap junction (GJ) channels provide an important pathway for direct intercellular transmission of signaling molecules. Previously we showed that fixed negative charges in the first extracellular loop domain (E1) strongly influence charge selectivity, conductance, and rectification of channels and hem...

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Detalles Bibliográficos
Autores principales: Kronengold, J., Trexler, E.B., Bukauskas, F.F., Bargiello, T.A., Verselis, V.K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233777/
https://www.ncbi.nlm.nih.gov/pubmed/12975451
http://dx.doi.org/10.1085/jgp.200308861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233777/
https://www.ncbi.nlm.nih.gov/pubmed/12975451
http://dx.doi.org/10.1085/jgp.200308861

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