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Dynamic Interaction of S5 and S6 during Voltage-Controlled Gating in a Potassium Channel

A gain-of-function mutation in the Caenorhabditis elegans exp-2 K(+)-channel gene is caused by a cysteine-to-tyrosine change (C480Y) in the sixth transmembrane segment of the channel (Davis, M.W., R. Fleischhauer, J.A. Dent, R.H. Joho, and L. Avery. 1999. Science. 286:2501–2504). In contrast to wild...

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Detalles Bibliográficos
Autores principales: Espinosa, Felipe, Fleischhauer, Richard, McMahon, Anne, Joho, Rolf H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233824/
https://www.ncbi.nlm.nih.gov/pubmed/11479343