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Molecular Architecture of the Voltage-Dependent Na Channel: Functional Evidence for α Helices in the Pore

The permeation pathway of the Na channel is formed by asymmetric loops (P segments) contributed by each of the four domains of the protein. In contrast to the analogous region of K channels, previously we (Yamagishi, T., M. Janecki, E. Marban, and G. Tomaselli. 1997. Biophys. J. 73:195–204) have sho...

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Detalles Bibliográficos
Autores principales: Yamagishi, Toshio, Li, Ronald A., Hsu, Kate, Marbán, Eduardo, Tomaselli, Gordon F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233827/
https://www.ncbi.nlm.nih.gov/pubmed/11479344