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Allosteric Regulation of Bk Channel Gating by Ca(2+) and Mg(2+) through a Nonselective, Low Affinity Divalent Cation Site
The ability of membrane voltage to activate high conductance, calcium-activated (BK-type) K(+) channels is enhanced by cytosolic calcium (Ca(2+)). Activation is sensitive to a range of [Ca(2+)] that spans over four orders of magnitude. Here, we examine the activation of BK channels resulting from ex...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233841/ https://www.ncbi.nlm.nih.gov/pubmed/11696615 |