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Distinct Mg(2+)-dependent Steps Rate Limit Opening and Closing of a Single CFTR Cl(−) Channel
The roles played by ATP binding and hydrolysis in the complex mechanisms that open and close cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channels remain controversial. In this work, the contributions made by ATP and Mg(2+) ions to the gating of phosphorylated cardiac CFTR channe...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233863/ https://www.ncbi.nlm.nih.gov/pubmed/12034762 http://dx.doi.org/10.1085/jgp.20028594 |