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Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 Channels

All members of the inward rectifiier K(+) (Kir) channel family are activated by phosphoinositides and other amphiphilic lipids. To further elucidate the mechanistic basis, we examined the membrane association of Kir6.2 fragments of K(ATP) channels, and the effects of site-directed mutations of these...

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Detalles Bibliográficos
Autores principales: Cukras, Catherine A., Jeliazkova, Iana, Nichols, Colin G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233865/
https://www.ncbi.nlm.nih.gov/pubmed/12034765
http://dx.doi.org/10.1085/jgp.20028562