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Dynamics of Ca(2+)-Calmodulin–dependent Inhibition of Rod Cyclic Nucleotide-gated Channels Measured by Patch-clamp Fluorometry

Cyclic nucleotide-gated (CNG) ion channels mediate cellular responses to sensory stimuli. In vertebrate photoreceptors, CNG channels respond to the light-induced decrease in cGMP by closing an ion-conducting pore that is permeable to cations, including Ca(2+) ions. Rod CNG channels are directly inhi...

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Detalles Bibliográficos
Autores principales: Trudeau, Matthew C., Zagotta, William N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233886/
https://www.ncbi.nlm.nih.gov/pubmed/15314069
http://dx.doi.org/10.1085/jgp.200409101