Cargando…

Angiotensin II (AT1) Receptors and NADPH Oxidase Regulate Cl(−) Current Elicited by β1 Integrin Stretch in Rabbit Ventricular Myocytes

Direct stretch of β1 integrin activates an outwardly rectifying, tamoxifen-sensitive Cl(−) current (Cl(−) SAC) via focal adhesion kinase (FAK) and/or Src. The characteristics of Cl(−) SAC resemble those of the volume-sensitive Cl(−) current, I(Cl,swell). Because myocyte stretch releases angiotensin...

Descripción completa

Detalles Bibliográficos
Autores principales: Browe, David M., Baumgarten, Clive M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233887/
https://www.ncbi.nlm.nih.gov/pubmed/15337822
http://dx.doi.org/10.1085/jgp.200409040