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Angiotensin II (AT1) Receptors and NADPH Oxidase Regulate Cl(−) Current Elicited by β1 Integrin Stretch in Rabbit Ventricular Myocytes
Direct stretch of β1 integrin activates an outwardly rectifying, tamoxifen-sensitive Cl(−) current (Cl(−) SAC) via focal adhesion kinase (FAK) and/or Src. The characteristics of Cl(−) SAC resemble those of the volume-sensitive Cl(−) current, I(Cl,swell). Because myocyte stretch releases angiotensin...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233887/ https://www.ncbi.nlm.nih.gov/pubmed/15337822 http://dx.doi.org/10.1085/jgp.200409040 |