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Structure–Function Relations of the First and Fourth Extracellular Linkers of the Type IIa Na(+)/P(i) Cotransporter: II. Substrate Interaction and Voltage Dependency of Two Functionally Important Sites

Functionally important sites in the predicted first and fourth extracellular linkers of the type IIa Na(+)/P(i) cotransporter (NaPi-IIa) were identified by cysteine scanning mutagenesis (Ehnes et al., 2004). Cysteine substitution or modification with impermeant and permeant methanethiosulfonate (MTS...

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Detalles Bibliográficos
Autores principales: Ehnes, Colin, Forster, Ian C., Bacconi, Andrea, Kohler, Katja, Biber, Jürg, Murer, Heini
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234003/
https://www.ncbi.nlm.nih.gov/pubmed/15504899
http://dx.doi.org/10.1085/jgp.200409061