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Structure–Function Relations of the First and Fourth Extracellular Linkers of the Type IIa Na(+)/P(i) Cotransporter: II. Substrate Interaction and Voltage Dependency of Two Functionally Important Sites
Functionally important sites in the predicted first and fourth extracellular linkers of the type IIa Na(+)/P(i) cotransporter (NaPi-IIa) were identified by cysteine scanning mutagenesis (Ehnes et al., 2004). Cysteine substitution or modification with impermeant and permeant methanethiosulfonate (MTS...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234003/ https://www.ncbi.nlm.nih.gov/pubmed/15504899 http://dx.doi.org/10.1085/jgp.200409061 |