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PKC-induced Sensitization of Ca(2+)-dependent Exocytosis Is Mediated by Reducing the Ca(2+) Cooperativity in Pituitary Gonadotropes

The highly cooperative nature of Ca(2+)-dependent exocytosis is very important for the precise regulation of transmitter release. It is not known whether the number of binding sites on the Ca(2+) sensor can be modulated or not. We have previously reported that protein kinase C (PKC) activation sensi...

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Detalles Bibliográficos
Autores principales: Yang, Hua, Liu, Huisheng, Hu, Zhitao, Zhu, Hongliang, Xu, Tao
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234013/
https://www.ncbi.nlm.nih.gov/pubmed/15710914
http://dx.doi.org/10.1085/jgp.200409230